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Fabio Candotti Selected Research

Adenosine Deaminase

10/2021Long-term outcomes after gene therapy for adenosine deaminase severe combined immune deficiency.
1/2021Autologous Ex Vivo Lentiviral Gene Therapy for Adenosine Deaminase Deficiency.
11/2020Adenosine Deaminase (ADA)-Deficient Severe Combined Immune Deficiency (SCID) in the US Immunodeficiency Network (USIDNet) Registry.
5/2015Outcomes in two Japanese adenosine deaminase-deficiency patients treated by stem cell gene therapy with no cytoreductive conditioning.
3/2014Early-onset stroke and vasculopathy associated with mutations in ADA2.
11/2012Gene therapy for adenosine deaminase-deficient severe combined immune deficiency: clinical comparison of retroviral vectors and treatment plans.
3/2012Multicentric dermatofibrosarcoma protuberans in patients with adenosine deaminase-deficient severe combined immune deficiency.
9/2011Myeloid dysplasia and bone marrow hypocellularity in adenosine deaminase-deficient severe combined immune deficiency.
7/2008Recent advances in gene therapy for severe congenital immunodeficiency diseases.
1/2007Prolonged pancytopenia in a gene therapy patient with ADA-deficient SCID and trisomy 8 mosaicism: a case report.
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Fabio Candotti Research Topics

Disease

13Wiskott-Aldrich Syndrome
10/2016 - 05/2003
12Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome)
10/2021 - 08/2002
12Severe combined immunodeficiency due to adenosine deaminase deficiency
10/2021 - 02/2002
5Neoplasms (Cancer)
01/2013 - 06/2002
4Primary Immunodeficiency Diseases
02/2014 - 11/2007
3X-Linked Combined Immunodeficiency Diseases (X Linked Severe Combined Immunodeficiency)
01/2013 - 01/2002
2Cytopenia
10/2021 - 09/2015
2Inflammation (Inflammations)
10/2016 - 07/2003
2Infections
12/2015 - 06/2004
2Thrombocytopenia 1
11/2015 - 02/2013
2Reticular dysgenesis
07/2015 - 01/2009
2Thrombocytopenia (Thrombopenia)
01/2015 - 01/2013
2Autoimmune Diseases (Autoimmune Disease)
06/2010 - 07/2007
2Colonic Neoplasms (Colon Cancer)
11/2002 - 06/2002
2Herpes Simplex
11/2002 - 06/2002
1Sarcoma (Soft Tissue Sarcoma)
10/2021
1Fetal Growth Retardation (Intrauterine Growth Retardation)
01/2021
1Body Weight (Weight, Body)
10/2020
1Agammaglobulinemia (Hypogammaglobulinemia)
04/2017
1Kidney Diseases (Kidney Disease)
01/2016
1Vomiting
12/2015
1Dehydration (Water Stress)
12/2015
1Fever (Fevers)
12/2015
1Protein Deficiency
10/2015
1Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune)
01/2015
1Schmid-Fraccaro syndrome
03/2014
1Immune System Diseases (Immune Disorders)
05/2013
1Genetic Translocation (Chromosomal Translocation)
03/2012
1Dermatofibrosarcoma
03/2012
1Lymphopenia (Lymphocytopenia)
09/2011
1Neutropenia
09/2011
1Glomerulonephritis
08/2010
1Retinoblastoma (Glioblastoma, Retinal)
06/2010
1Communicable Diseases (Infectious Diseases)
12/2009
1Rare Diseases (Rare Disease)
12/2009
1Deafness (Deaf Mutism)
01/2009
1Chronic Granulomatous Disease
07/2008
1Cartilage-hair hypoplasia
11/2007
1Pancytopenia
01/2007
1Epstein-Barr Virus Infections
08/2003
1Disease Progression
08/2003
1Lymphoproliferative Disorders (Lymphoproliferative Disorder)
08/2003
1Vasculitis (Vasculitides)
07/2003
1Autoimmune Hemolytic Anemia (Cold Agglutinin Disease)
07/2003

Drug/Important Bio-Agent (IBA)

13Adenosine DeaminaseIBA
10/2021 - 02/2002
10Proteins (Proteins, Gene)FDA Link
03/2012 - 05/2003
5AutoantibodiesIBA
01/2016 - 08/2010
2Busulfan (Busulfex)FDA Link
10/2021 - 10/2020
2Pharmaceutical PreparationsIBA
10/2020 - 11/2002
2Immunoglobulin E (IgE)IBA
10/2016 - 12/2013
2Inosine Triphosphate (ITP)IBA
01/2015 - 01/2013
2Cytokine Receptors (Cytokine Receptor)IBA
01/2013 - 11/2006
2RNA (Ribonucleic Acid)IBA
01/2013 - 11/2007
2Anti-Bacterial Agents (Antibiotics)IBA
09/2011 - 06/2004
2Wiskott-Aldrich Syndrome ProteinIBA
11/2007 - 02/2007
2ThymidineIBA
11/2002 - 06/2002
2(north)-methanocarbathymidineIBA
11/2002 - 06/2002
2ProdrugsIBA
11/2002 - 06/2002
2Thymidine KinaseIBA
11/2002 - 06/2002
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
10/2021
1VaccinesIBA
04/2017
1Immunoglobulins (Immunoglobulin)IBA
04/2017
1AllergensIBA
10/2016
1AntigensIBA
01/2016
1Adenosine (Adenocard)FDA LinkGeneric
12/2015
1Transaminases (Aminotransferases)IBA
12/2015
1AntibodiesIBA
10/2015
1IsoenzymesIBA
07/2015
1T-Cell Antigen Receptors (T-Cell Receptor)IBA
05/2013
1Peptide LibraryIBA
05/2013
1Immunoglobulin A (IgA)IBA
02/2013
1OligodeoxyribonucleotidesIBA
01/2013
1CyclinsIBA
01/2013
1Transcription Factors (Transcription Factor)IBA
01/2013
1Proto-Oncogene Proteins c-sis (Platelet Derived Growth Factor B)IBA
03/2012
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
03/2012
1Antigen-Antibody Complex (Immune Complex)IBA
08/2010
1ChromatinIBA
06/2010
1Carrier Proteins (Binding Protein)IBA
06/2010
1gamma-Globulins (gamma-Globulin)IBA
12/2009
1ElementsIBA
12/2009
1purineIBA
10/2009
1adenylate kinase 2IBA
01/2009
1Growth Hormone (Somatotropin)IBA
11/2006
1Signaling Lymphocytic Activation Molecule Associated ProteinIBA
08/2003
1Interleukin-2 (IL2)IBA
07/2003
1AutoantigensIBA
07/2003
1Complementary DNA (cDNA)IBA
04/2003
15- carboxy- methylaminomethyl- 2'- O- methyluridineIBA
11/2002
1EnzymesIBA
11/2002
1Bovine Serum AlbuminIBA
09/2002

Therapy/Procedure

7Therapeutics
01/2015 - 01/2002
3Enzyme Replacement Therapy
10/2021 - 10/2009
2Hematopoietic Stem Cell Transplantation
10/2021 - 12/2009
1Protein-Restricted Diet (Diet, Protein Restricted)
01/2021
1Investigational Therapies (Experimental Therapy)
09/2011
1Drug Therapy (Chemotherapy)
09/2011
1Transplantation
12/2009
1Stem Cell Transplantation
10/2009
1Bone Marrow Transplantation (Transplantation, Bone Marrow)
07/2003